HIDRADENITIS SUPPURATIVA

Jun
2017
Vol. 36. No. 2

Introduction

Haley Naik, MD, MHSc

In this issue of Seminars in Cutaneous Medicine and Surgery, we focus on providing readers with a comprehensive understanding of the current state of knowledge, as well as major knowledge gaps, of HS.

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View AllGUEST EDITOR

Assistant Professor
Department of Dermatology
University of California, San Francisco

Seminars in Cutaneous Medicine and Surgery
publishes peer-reviewed information on the diagnosis and management of specific disorders of the skin, as well as the application of the latest scientific findings to patient care.
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What’s new in acne and rosacea? Jun 2016 | Vol. 35 | No. 2

Acne and rosacea are common conditions seen every day by dermatologists. This review will discuss the most recent therapeutic options for patients with these conditions. Specifically, for acne, there will be a discussion of the use of isotretinoin at higher cumulative doses as well as a new formulation of isotretinoin, isotretinoin-lidose. Adult women with acne represent a growing population of patients who present for treatment of acne; the use of hormonal therapies as well as topical dapsone gel will be reviewed for these patients. For rosacea patients, the new topical agents – brimonidine gel and ivermectin cream – will be reviewed, with a discussion on possible rebound phenomenon from brimonidine. Finally, future treatments in the pipeline will be discussed.

Semin Cutan Med Surg 35:103-106 © 2016 Frontline Medical Communications

Current state of imaging in dermatology Mar 2016 | Vol. 35 | No. 1

Medical imaging has dramatically transformed the practice of medicine, especially the field of dermatology. Imaging is used to facilitate the transfer of information between providers, document cutaneous disease, assess response to therapy, and plays a crucial role in monitoring and diagnosing skin cancer. Advancements in imaging technology and overall improved quality of imaging have augmented the utility of photography. We provide an overview of current imaging technologies used in dermatology with a focus on their role in skin cancer diagnosis. Future technologies include three-dimensional, total-body photography, mobile smartphone applications, and computerassisted diagnostic devices. With these advancements, we are better equipped to capture and monitor skin conditions longitudinally and achieve improved diagnostic accuracy of skin cancer.


Semin Cutan Med Surg 35:2-8 © 2016 Frontline Medical
Communications

Differential diagnosis and management of oral ulcers Dec 2015 | Vol. 34 | No. 4

The diagnosis and treatment of oral lesions is often challenging due to the clinician’s limited exposure to the conditions that may cause the lesions and their similar appearances. While many oral ulcers are the result of chronic trauma, some may indicate an underlying systemic condition such as a gastrointestinal dysfunction, malignancy, immunologic abnormality, or cutaneous disease. Correctly establishing a definitive diagnosis is of major importance to clinicians who manage patients with oral mucosal disease. Some of these diseases are infectious; however, most are chronic, symptomatic, and desquamative. Treatment and management requires an understanding of the immunopathologic nature of the lesion. This review will address how to differentiate and diagnose varying types of oral ulcers and provide a treatment strategy. 
Semin Cutan Med Surg 34:171-177 © 2015 Frontline Medical Communications

Alopecia areata update Jun 2015 | Vol. 34 | No. 2

There is neither a cure for alopecia areata (AA) nor any universally proven therapy that induces and sustains remission in patients afflicted with this autoimmune disease. AA is characterized as a nonscarring alopecia which affects children and adults. It can be relatively easy to treat when the disease is patchy and limited; but when children and adults present with long standing extensive scalp and body hair loss, successful management can be challenging. Of the treatment choices available, physicians and midlevel providers usually select a cost-effective treatment approach based on disease duration, disease activity, age of the patient, and disease extent. In this manuscript, the clinical presentation, epidemiology, pathophysiology, plus current and evolving treatments for AA will be reviewed. Semin Cutan Med Surg 34:72-75 © 2015 Frontline Medical Communications

Neuropathic Itch Jun 2011 | Vol. 30 | No. 2

Chronic itch can be caused by dysfunctions of itch-sensing neurons that produce sensory
hallucinations of pruritogenic stimuli. The cellular and molecular mechanisms are still
unknown. All neurological disease categories have been implicated, and neurological
causes should be considered for patients with otherwise-unexplained itch. The same
neurological illnesses that cause neuropathic pain can also or instead cause itch. These
include shingles (particularly of the head or neck), small-fiber polyneuropathies, radiculopathies
(eg, notalgia paresthetica and brachioradial pruritis), and diverse lesions of the
trigeminal nerve, root, and central tracts. Central nervous system lesions affecting sensory
pathways, including strokes, multiple sclerosis, and cavernous hemangiomas, can cause
central itch. Neuropathic itch is a potent trigger of reflex and volitional scratching although
this provides only fleeting relief. Rare patients whose lesion causes sensory loss as well as
neuropathic itch can scratch deeply enough to cause painless self-injury. The most common
location is on the face (trigeminal trophic syndrome). Treating neuropathic itch is
difficult; antihistamines, corticosteroids, and most pain medications are largely ineffective.
Current treatment recommendations include local or systemic administration of inhibitors
of neuronal excitability (especially local anesthetics) and barriers to reduce scratching.
Semin Cutan Med Surg 30:87-92 © 2011 Elsevier Inc. All rights reserved.

Statement of Purpose

Seminars in Cutaneous Medicine and Surgery presents well-rounded and authoritative discussions of important clinical areas, especially those undergoing rapid change in the specialty. Each issue, under the direction of the Editors and Guest Editors selected because of their expertise in the subject area, includes the most current information on the diagnosis and management of specific disorders of the skin, as well as the application of the latest scientific findings to patient care.

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