Nathan S. Uebelhoer

Guest Editor for the following articles:

Mar
2015
Vol. 34. No. 1

An idiosyncratic history of burn scars

Jane A Petro, MD
The ability to detect early melanoma remains of paramount importance in our efforts to curtail deaths related to this malignancy. Fortunately, our clinical skills at recognizing the varied clinical presentation of early melanomas are continuously improving. Our enhanced clinical acumen together with improved awareness of the danger signs of melanoma has resulted in a greater proportion of thin melanomas being diagnosed today as compared to the past. The implementation and utilization of in vivo imaging technologies in clinical practice promises to further enhance our ability to detect melanoma while this cancer is still thin and easily curable. This article describes the utility and application of the in vivo imaging technologies that are currently in clinical use today including dermoscopy, total body photography, individual lesion photography, and reflectance confocal microscopy. Semin Cutan Med Surg 27:2-10 © 2008 Elsevier Inc. All rights reserved.
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Dec
2008
Vol. 27. No. 4

Light-Emitting Diodes (LEDs) in Dermatology

Daniel Barolet, MD

Light-emitting diode photobiomodulation is the newest category of nonthermal light therapies
to find its way to the dermatologic armamentarium. In this article, we briefly review
the literature on the development of this technology, its evolution within esthetic and
medical dermatology, and provide practical and technical considerations for use in various
conditions. This article also focuses on the specific cell-signaling pathways involved and
how the mechanisms at play can be put to use to treat a variety of cutaneous problems as
a stand-alone application and/or complementary treatment modality or as one of the best
photodynamic therapy light source.
Semin Cutan Med Surg 27:227-238 © 2008 Elsevier Inc. All rights reserved.

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Dec
2008
Vol. 27. No. 4

Fractional Carbon Dioxide Laser and Plasmakinetic Skin Resurfacing

Nathan S Uebelhoer, DO | Richard E. Fitzpatrick, MD, FAAD | William F. Groff, DO, FAAD

Photodamage is one of the most common reasons that patients visit a dermatologist’s
office. Carbon dioxide (CO2) laser resurfacing has always been the gold standard for
reversing photodamage. Because of the relatively high incidence of side effects and the
prolonged downtime associated with CO2 resurfacing, new technologies have emerged to
address photodamage. Portrait skin regeneration (PSR) is a novel device that has been
developed to treat photodamage, and this device yields fewer side effects and downtime
than traditional CO2 laser resurfacing. At our center, we have performed more than 500
high-energy PSR treatments and have developed a unique and highly effective treatment
protocol. In addition, fractional CO2 laser resurfacing has emerged as the latest technology
developed to combat photoaging. This technology yields impressive results and is much
safer and causes less downtime than traditional CO2 laser resurfacing. In this article, we
will review our treatment techniques and protocols as well as address patient selection,
preoperative and postoperative care, and anesthesia.
Semin Cutan Med Surg 27:239-251 © 2008 Elsevier Inc. All rights reserved.

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Mar
2015
Vol. 34. No. 1

Microstructural and molecular considerations in the treatment of scars with ablative fractional lasers

Cerrene N Giordano, MD | David Ozog, MD
Fractional ablative lasers have recently proven to be an effective modality for improving the clinical appearance and minimizing the morbidity associated with restrictivetype scars. Their tolerable safety profile on nonfacial sites and darker Fitzpatrick skin types provides an advantage over its fully ablative counterpart in treating facial rhytides, photodamaged skin, and acne scars. However, despite its increasing usage in clinical practice, the mechanism behind the observed clinical benefit remains complex and has yet to be fully elucidated. This paper reviews the work on the histological mechanism of action of ablative fractional lasers, and the molecular changes that occur posttreatment on restrictive scars, with an emphasis on mature burn and postsurgical scars. As the majority of research has been on the carbon dioxide laser, a natural focus on this wavelength is presented. Semin Cutan Med Surg 34:7-12 © 2015 Frontline Medical Communications
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Mar
2015
Vol. 34. No. 1

Current trends and future considerations in scar treatment

Ashley Rudnick | Jill S Waibel, MD
The goal of scar therapy is the restoration of the patient to their preinjury state. A combination of injected antimetabolites, surgery, laser, and laser-assisted delivery of drugs is needed for minimally invasive surgical correction of scars. As a result, laser therapy is emerging as an essential treatment element. It has been noted that fractional lasers normalize both the clinical and histological appearance of scars. Laser- and light-based therapies complement existing approaches of surgery and physical therapy, resulting in significant gains with minimal associated morbidity. Emerging and future laser technologies are creating a new paradigm in the management of scar rehabilitation. Semin Cutan Med Surg 34:13-16 © 2015 Frontline Medical Communications
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