Andrei I. Metelitsa

Guest Editor for the following articles:

Sep
2011
Vol. 30. No. 3

Cosmeceuticals for Cellulite

Doris Hexsel, MD
Cellulite is characterized by alterations to the skin surface, presenting as dimpled or puckered skin of the buttocks and posterior and lateral thighs. It mainly affects women. Cellulite occurrence is believed to be due to structural, inflammatory, morphological and biochemical alterations of the subcutaneous tissue. However, its pathogenesis is not completely understood. Topical treatments for cellulite include many agents, such those that increase the microcirculation flow, agents that reduce lipogenesis and promote lipolysis, agents that restore the normal structure of dermis and subcutaneous tissue, and agents that scavenge free radicals or prevent their formation. There are many cosmetic and medical treatments for cellulite. However, there is little clinical evidence of an improvement in cellulite, and none have been shown to lead to its resolution. The successful treatment of cellulite will ultimately depend upon our understanding of the physiopathology of cellulite adipose tissue. Semin Cutan Med Surg 30:167-170 © 2011 Elsevier Inc. All rights reserved.
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Sep
2011
Vol. 30. No. 3

Treatment of Hyperpigmentation

Heather Woolery-Lloyd, MD
Hyperpigmentation is a common dermatologic condition that is seen in all skin types but is most prominent in skin of color. In skin of color, any inflammation or injury to skin can almost immediately be accompanied by alterations in pigmentation, either hyperpigmentation or hypopigmentation. Post-inflammatory hyperpigmentation can be observed in many skin conditions including acne, eczema, and contact dermatitis and treatment can be challenging. The goal is to reduce the hyperpigmentation without causing undesirable hypopigmentation or irritation in the surrounding area. This review will discuss current research on treatments for hyperpigmentation and approaches to treating this condition. Semin Cutan Med Surg 30:171-175 © 2011 Elsevier Inc. All rights reserved.
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Sep
2011
Vol. 30. No. 3

Nanotechnology Use with Cosmeceuticals

Bhavdeep Shah, PhD | Nevenka Golubovic-Liakopoulos, PhD
The skin is a complex organ and its aging is a complex process. Cutaneous aging is influenced by factors such as sun exposure, genetics, stress and the environment. While skin laxity, rhytides, and dyschromia appear on the surface, these processes originate in deeper layers including the dermis and subcutaneous tissues. Until recently, most topical skin treatments were applied to, and consequently only affected the skin surface. Skin care has evolved to be scientifically based, and as knowledge increases about the physiology of the skin, novel methods of maintaining its health and appearance are developed. New generation skin care products are targeting multiple aging mechanisms by utilizing functional active ingredients in combination with innovative delivery systems. Semin Cutan Med Surg 30:176-180 © 2011 Elsevier Inc. All rights reserved.
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Sep
2011
Vol. 30. No. 3

Erratum

SCMS: Seminars in Cutaneous Medicine and Surgery
In the June 2011 article “Approach to Pruritus in the Adult HIV-Positive Patient” (vol 30, no 2, pages 101-106), the first author’s name was listed incorrectly. It should be listed as follows: Ser Ling Chua.
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