PRECISION MEDICINE
Prospects for personalized targeted therapies for cutaneous squamous cell carcinoma
Jun
2014
Vol. 33. No. 2
Targeted therapies for cutaneous squamous cell carcinoma
(cSCC) remain limited. Extensive genetic heterogeneity
complicates a robust molecular characterization
of the evolution of cSCC. Nonetheless, potential targeted
therapies for this cancer are under investigation, including
the inhibition of epidermal growth factor receptor
(EGFR), which may yield promising results. In addition, the
emergence of immune checkpoint blockade therapy
and vaccine-based methods may provide novel treatment
strategies for cSCC that are tailored to the individual
patient. Ultimately, a combination of such methods may
yield a multi-pronged targeted approach to personalize
the treatment of cSCC.
Semin Cutan Med Surg 33:72-75 © 2014 Frontline Medical
Communications
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