COSMECEUTICALS: CURRENT TRENDS AND MARKET ANALYSIS
Innovative Cosmeceuticals: Sirtuin Activators and Anti-Glycation Compounds
Sep
2011
Vol. 30. No. 3
Skin aging is a combination of natural aging with superimposed photoaging. Naturally aged
skin is thin, fragile and finely wrinkled whereas photoaged skin is rough and thickened with
deep coarse wrinkles. In addition photoaging is characterized by mottled pigmentation,
solar lentigines, telangectasias and a loss of elasticity. The science behind skin aging has
exploded in the past decade. Skin aging has now been defined on both a cellular and
molecular level. The study of genomics in aging skin provides us with potential targets as
points for intervention. In this regard, the science behind skin aging becomes a platform for
the development of new anti-aging strategies and products. In this paper two new and
emerging approaches to treat aging skin will be discussed. Sirtuin activating and antiglycation
products are already being marketed by cosmetic and pharmaceutical companies.
These anti-aging approaches are backed by basic science research and the ingredients
used are supported by proof of concept studies although clinical trials are often lacking. It
is this bench to beauty counter approach to cosmeceuticals that remains an industry
standard today.
Semin Cutan Med Surg 30:163-166 © 2011 Elsevier Inc. All rights reserved.
PURCHASE NOW