BULLOUS DISORDERS & MALIGNANT CUTANEOUS TUMORS
Introduction
DESPITE THE STUNNING ACHIEVEMENTS and the promise afforded by all things concerning our genes and theirĀ transcribed proteins, such time-honored technologies as histology and the principle of clinico-pathologic correlation endure today in the practice of dermatology as it did nearly 100 years ago. Shapes, colors, and the pattern evoked by pathologic change in histologic sections of tissue captivate not only our visual sense, they prevail as both the fundamental method of diagnostic discernment and the forerunner of pathogenic assignment. The practice and practicality of dermatopathology as forged by the likes of Helwig, Lever, and Ackerman will continue to thrive into the foreseeable future.
Bullous Disorders & Malignant Cutaneous Tumors, Introduction
DESPITE THE STUNNING ACHIEVEMENTS and the promise afforded by all things concerning our genes and their transcribed proteins, such time-honored technologies as histology and the principle of clinico-pathologic correlation endure today in the practice of dermatology as it did nearly 100 years ago.
The Intraepidermal Blistering Conditions
The intraepidermal vesiculobullous disorders constitute a wide variety of pathogenically unrelated disorders that share in common the formation of cleft or bullae formation within the epithelium.
Subepidermal Blistering Disorders: A Clinical and Histopathologic Review
The subepidermal blistering disorders are comprised of a number of unrelated disorders with a diverse clinical presentation and pathogenic basis that share in common the presence of blister formation beneath the epidermis. Many of the disorders are both debilitating and potentially fatal.
The Miscellaneous Blistering Disorders
Historically, the classification of the blistering disorders has been arbitrarily assigned by common clinical features (ie, vesicle, bullae), etiologic factors (ie, infectious, immunologic), or histologic parameters (ie, intraepidermal and subepidermal).
The Pustular Disorders
VESICULOBULLOUS DERMATOSES are a group of disorders resulting in vesicle or bulla formation within the epidermis or within the dermoepidermal junction.