BIOLOGIC AGENTS FOR PSORIASIS

Mar
2005
Vol. 24. No. 1

Introduction

Since the late 1990s, the use of biologics for psoriasis has been showcased in the dermatology literature and in educational meetings. Most of the literature has focused on the safety and efficacy data generated from clinical trials. The aim of this issue is to take this discussion one step further and examine the incorporation of these agents successfully into clinical practice.

The Treatment of Psoriasis with Etanercept

Bruce E. Strober, MD, PhD

This chapter reviews etanercept (EnbrelĀ®, Amgen and Wyeth, Thousand Oaks, CA), the first TNF- inhibitor approved by the Food and Drug Administration (FDA) for the treatment of not only plaque psoriasis but also psoriatic arthritis (PsA). Both efficacy and safety data for etanercept will be discussed, and a practical approach for the use of this drug in the dermatologic practice will be outlined.

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