Skin Grafting
ALTHOUGH SKIN GRAFTING originated 2500 to 3000 years ago, it was not until the 19th century that this technique was again introduced as a reconstructive option.
The Role of Targeted Molecular Inhibitors in the Management of Advanced Nonmelanoma Skin Cancer
Surgical treatment remains the standard of care for nonmelanoma skin cancer and is
successful for the vast majority of patients with these tumors. The treatment of patients
with metastatic or unresectable nonmelanoma skin cancer, however, has until recently
been based solely on traditional methods of chemotherapy and radiation. However, these
methods have high rates of treatment failure, morbidity, and mortality, and alternative
treatment modalities for patients with aggressive or advanced disease are needed. As in
other areas of cancer therapeutics, recent research elucidating the molecular basis of
cancer development, and the subsequent arrival of targeted molecular inhibitors for cancer
therapy, have been met with much excitement. In this review, we seek to illuminate recent
developments and future possibilities in the use of targeted molecular inhibitors for
treatment of advanced squamous cell carcinoma, basal cell carcinoma, and dermatofibrosarcoma
protuberans.
Semin Cutan Med Surg 30:57-61 © 2011 Published by Elsevier Inc.
Techniques for Cutaneous Sutured Closures: Variants and Indications
This review describes suture methods that represent the versatility of basic techniques, including consensuses and controversies among authors regarding indications for usage.