Cutaneous Lymphoid Hyperplasias
Benign hypetplastic lymphoid Infiltrates of the skin (pseudolymphoma, older term) simulate lymphoma clinically and histologically. They can be divided into B-cell predominant (typical cutaneous lymphoid hyperplasia (CLH], angiolymphoid hyperplasia, Kimura’s disease, and Castleman’s disease) and T-cell predominant (T-cell CLH, lymphomatoid contact dermatitis, and lymphomatoid drug eruption).
Treatment of Cutaneous T-Cell Lymphomas
PRIMARY CUTANEOUS T-cell lymphomas (CTCL) represent a heterogeneous group of non-Hodgkin’s lymphomas (NHL), which show a considerable variation in clinical presentation, histology, immunophenotype, and prognosis.
New Developments in Extracutaneous Lymphomas
This review focuses on the modem approach to lymphoma diagnosis, discusses new insights into lymphoma biology and pathogenesis, and outlines current therapeutic strategies. All of these aspects will mainly deal with the most frequently encountered lymphoid neoplasms, which are of B-cell origin.
Controversies in Cutaneous Lymphomas
In this article the following topics are reviewed: (1) Classification of cutaneous lymphomas; (2) Cutaneous T-cell lymphoma with small/medium-sized pleomorphic cells as a distinct entity; (3) Primary cutaneous follicle center lymphoma and marginal zone lymphoma/immunocytoma.