Sep
2011
Vol. 30. No. 3
Cosmeceuticals for Cellulite
Cellulite is characterized by alterations to the skin surface, presenting as dimpled or
puckered skin of the buttocks and posterior and lateral thighs. It mainly affects women.
Cellulite occurrence is believed to be due to structural, inflammatory, morphological and
biochemical alterations of the subcutaneous tissue. However, its pathogenesis is not
completely understood. Topical treatments for cellulite include many agents, such those
that increase the microcirculation flow, agents that reduce lipogenesis and promote lipolysis,
agents that restore the normal structure of dermis and subcutaneous tissue, and
agents that scavenge free radicals or prevent their formation. There are many cosmetic and
medical treatments for cellulite. However, there is little clinical evidence of an improvement
in cellulite, and none have been shown to lead to its resolution. The successful treatment
of cellulite will ultimately depend upon our understanding of the physiopathology of
cellulite adipose tissue.
Semin Cutan Med Surg 30:167-170 © 2011 Elsevier Inc. All rights reserved.
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Sep
2011
Vol. 30. No. 3
Treatment of Hyperpigmentation
Hyperpigmentation is a common dermatologic condition that is seen in all skin types but is
most prominent in skin of color. In skin of color, any inflammation or injury to skin can
almost immediately be accompanied by alterations in pigmentation, either hyperpigmentation
or hypopigmentation. Post-inflammatory hyperpigmentation can be observed in many
skin conditions including acne, eczema, and contact dermatitis and treatment can be
challenging. The goal is to reduce the hyperpigmentation without causing undesirable
hypopigmentation or irritation in the surrounding area. This review will discuss current
research on treatments for hyperpigmentation and approaches to treating this condition.
Semin Cutan Med Surg 30:171-175 © 2011 Elsevier Inc. All rights reserved.
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Sep
2011
Vol. 30. No. 3
Nanotechnology Use with Cosmeceuticals
The skin is a complex organ and its aging is a complex process. Cutaneous aging is
influenced by factors such as sun exposure, genetics, stress and the environment. While
skin laxity, rhytides, and dyschromia appear on the surface, these processes originate in
deeper layers including the dermis and subcutaneous tissues. Until recently, most topical
skin treatments were applied to, and consequently only affected the skin surface. Skin care
has evolved to be scientifically based, and as knowledge increases about the physiology of
the skin, novel methods of maintaining its health and appearance are developed. New
generation skin care products are targeting multiple aging mechanisms by utilizing functional
active ingredients in combination with innovative delivery systems.
Semin Cutan Med Surg 30:176-180 © 2011 Elsevier Inc. All rights reserved.
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Sep
2011
Vol. 30. No. 3