Hidradenitis suppurativa (HS) is an inflammatory skin disorder with many associated comorbidities, including obesity, metabolic syndrome, smoking, depression, arthritis, autoinflammatory syndromes, inflammatory bowel disease, and genetic syndromes. In addition, HS patients can suffer from a variety of diseases related to the chronic inflammatory nature of their HS such as cardiovascular disease and anemia. An understanding of these comorbidities and associations is essential for the management of HS, and routine screening for these entities should be considered in all HS patients.

Porter ML, Kimball AB. Comorbidities of hidradenitis suppurativa. Sem Cutan Med Surg. 2017;36(2):55-57. https://doi.org/10.12788/j.sder.2107.018.

Hidradenitis suppurativa (HS) is associated with multiple comorbidities, including metabolic syndrome, smoking, depression, the follicular occlusion tetrad, genetic syndromes, malignancy, and autoimmune diseases (ie, inflammatory bowel disease (IBD), arthritis, and spondyloarthropathy). Additionally, due to the persistent inflammation and chronic nature of the disease, patients may experience a variety of other conditions that may be a result of the disease process itself (ie, depression, anxiety, anemia, and cardiovascular disease).