Topical Therapy in Pediatric Atopic Dermatitis

With a prevalence of 10% to 20% in the first decade of life, atopic dermatitis (AD) is one
of the most common skin disorders in young children. It is a chronic illness with limited
therapeutic options. Topical anti-inflammatory agents remain at the core of medical management;
however, their efficacy must be balanced with safety concerns, especially as they
relate to the pediatric population. This article discusses the principles of topical AD therapy
with a detailed review of the differences between topical corticosteroids and topical
calcineurin inhibitors. It also includes specialized topical treatment strategies for AD, such
as wet wraps and diluted bleach baths, and highlights the most common challenges to
patient compliance in atopic dermatitis.
Semin Cutan Med Surg 27:161-167 © 2008 Elsevier Inc. All rights reserved.

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