Approach to Pruritus in the Adult HIV-Positive Patient

Pruritus will affect a majority of HIV-infected adults in the course of their disease, impacting
their quality of life. Itchy skin conditions in the HIV-infected patient may be atypical in
appearance and pose diagnostic and treatment challenges. Skin changes because of
chronic scratching or the absence of skin findings despite ongoing pruritus should prompt
investigations for underlying causes. The presence of pruritus or pruritic skin conditions
and their response to therapy may be a barometer for changes in systemic inflammation,
immune activation, and dysregulation because of infection with HIV and treatment with
antiretroviral therapy.
Semin Cutan Med Surg 30:101-106 © 2011 Elsevier Inc. All rights reserved.

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