Commercial sunscreen based on nano-sized titanium dioxide (TiO2) and zinc oxide (ZnO)
delivers superior UV protection and reduces whitening on skin compared to the older
generations of inorganic sunscreens. This review discusses the historical use of nano-sized
TiO2 and ZnO in sunscreen and the relationship between UV attenuation and the primary
particles, aggregates and agglomerates that make up these inorganic oxides. In addition we
reviewed the recent safety concerns surrounding these materials, specifically, percutaneous
penetration of TiO2 and ZnO nanoparticles through human skin and their potential to
cause phototoxicity.
Semin Cutan Med Surg 30:210-213 © 2011 Elsevier Inc. All rights reserved.Commercial sunscreen based on nano-sized titanium dioxide (TiO2) and zinc oxide (ZnO)
delivers superior UV protection and reduces whitening on skin compared to the older
generations of inorganic sunscreens. This review discusses the historical use of nano-sized
TiO2 and ZnO in sunscreen and the relationship between UV attenuation and the primary
particles, aggregates and agglomerates that make up these inorganic oxides. In addition we
reviewed the recent safety concerns surrounding these materials, specifically, percutaneous
penetration of TiO2 and ZnO nanoparticles through human skin and their potential to
cause phototoxicity.
Semin Cutan Med Surg 30:210-213 © 2011 Elsevier Inc. All rights reserved.