ADVANCES IN LASER SCAR REHABILITATION
Microstructural and molecular considerations in the treatment of scars with ablative fractional lasers
Mar
2015
Vol. 34. No. 1
Fractional ablative lasers have recently proven to be an
effective modality for improving the clinical appearance
and minimizing the morbidity associated with restrictivetype
scars. Their tolerable safety profile on nonfacial sites
and darker Fitzpatrick skin types provides an advantage
over its fully ablative counterpart in treating facial rhytides,
photodamaged skin, and acne scars. However, despite
its increasing usage in clinical practice, the mechanism
behind the observed clinical benefit remains complex
and has yet to be fully elucidated. This paper reviews the
work on the histological mechanism of action of ablative
fractional lasers, and the molecular changes that occur
posttreatment on restrictive scars, with an emphasis on
mature burn and postsurgical scars. As the majority of
research has been on the carbon dioxide laser, a natural
focus on this wavelength is presented.
Semin Cutan Med Surg 34:7-12 © 2015 Frontline Medical
Communications
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